Hepatitis B Test Panel
A comprehensive blood test panel that checks for current hepatitis B infection, immunity status, and past exposure through three key markers.
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What this test measures
This comprehensive hepatitis B panel tests three important markers that work together to provide a complete picture of hepatitis B status. The HBV Surface Antigen (HBsAg) is a protein on the surface of the hepatitis B virus that indicates current infection and infectiousness. The HBV Surface Antibody (anti-HBs) indicates immunity from vaccination or recovery from past infection. The HBV Core Antibody (anti-HBc) appears at infection onset and persists for life, indicating any exposure to the virus.
The CDC recommends that all adults aged 18 and older receive hepatitis B screening at least once in their lifetime using this type of triple panel test. Understanding all three markers together helps determine whether someone has never been exposed to hepatitis B, is currently infected, has recovered with immunity, or has been successfully vaccinated. This information is essential for making informed decisions about vaccination needs, monitoring infection status, and protecting both personal health and the health of others.
What's included
Who should consider this test
You might consider this test if you are experiencing any of the following:
- Adults who have never been tested for hepatitis B and want to know their status
- People with multiple sexual partners or those whose partners have multiple partners
- Men who have sex with men
- People who inject drugs or share needles, syringes, or other drug equipment
- Household contacts or sexual partners of people with hepatitis B
- Healthcare and public safety workers exposed to blood
- People on dialysis or with kidney disease
- Individuals born in regions with high hepatitis B rates
- People with HIV or hepatitis C infection
What to expect
Preparation
No fasting or special preparation required. Avoid biotin supplements for 24 hours before testing.
Sample Type
A simple blood draw from a vein in the arm, taking just a few minutes
Collection
Visit any lab location with your test order, provide ID, and have blood drawn by trained staff
Turnaround
Results typically available within 1-3 business days through secure online portal
Understanding your results
The results of the three tests (HBsAg, anti-HBs, and anti-HBc) work together to indicate hepatitis B status and immunity level. Your lab report will show whether each marker is positive (reactive) or negative (non-reactive), along with quantitative values where applicable. The specific combination of results determines whether you have immunity, current infection, past exposure, or need vaccination.
| Population | Reference Range | Notes |
|---|---|---|
| HBV Surface Antigen | Negative/Non-reactive | Positive indicates current infection |
| HBV Surface Antibody | ≥10 mIU/mL protective | Indicates immunity from vaccination or recovery |
| HBV Core Antibody | Negative/Non-reactive | Positive indicates past or current exposure |
Reference ranges shown are general guidelines. Your lab report will include the specific reference range used by the laboratory that processed your sample, which is the authoritative range for interpreting your results.
What does a “Low” result mean?
Negative results for all three markers typically indicate no current infection and no immunity, suggesting vaccination may be beneficial. Surface antibody levels below 10 mIU/mL indicate lack of adequate immune protection. Negative core antibody indicates no previous exposure to hepatitis B virus.
What does a “High” result mean?
A positive surface antigen may indicate current hepatitis B infection and the ability to transmit the virus to others. A positive surface antibody (≥10 mIU/mL) indicates immunity from vaccination or recovery from past infection. A positive core antibody may indicate acute, chronic, or past resolved hepatitis B.
Privacy & confidentiality
Your hepatitis B test results are completely confidential and delivered securely through your private online account. Results are not shared with employers, insurance companies, or anyone else without your explicit consent. All testing is conducted with complete discretion and privacy protection.
Frequently asked questions
Related tests
CPT Code: 87340, 86706, 86707
This test may not be available in: NY, NJ, RI
This page is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider regarding any health concerns. LevelPanel does not diagnose, treat, or prescribe.
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Not sure if this is the right test? Contact our care team for guidance.