Hepatitis C Test
This test screens for hepatitis C virus (HCV) antibodies to detect past or current infection, with automatic RNA testing if antibodies are found.
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What this test measures
This test screens for antibodies to the hepatitis C virus (HCV), which indicates whether someone has been exposed to or infected with the virus. The initial test uses an antibody screening assay that detects proteins your immune system produces when exposed to hepatitis C. If antibodies are detected, the lab automatically performs a follow-up RNA test to determine if the virus is currently active in your body. This two-step process is essential because approximately 15-25% of people naturally clear the hepatitis C virus on their own, but still retain antibodies for life. The antibody test cannot distinguish between past resolved infection and current active infection, which is why RNA testing is performed when antibodies are found. This comprehensive screening approach provides accurate results about both exposure history and current infection status, allowing for appropriate medical follow-up when needed.
Who should consider this test
You might consider this test if you are experiencing any of the following:
- Adults born between 1945-1965, as this generation has the highest rates of hepatitis C infection
- People who have ever used injection drugs, even if only once or many years ago
- Individuals who received blood transfusions or organ transplants before 1992, when screening began
- People with HIV infection or other sexually transmitted infections
- Healthcare workers or first responders with potential blood exposure
- Anyone with unexplained liver problems or elevated liver enzymes
- People seeking comprehensive STD screening or routine health checkups
- Partners of individuals known to have hepatitis C infection
What to expect
Preparation
No special preparation is needed. You can eat normally and take medications as usual.
Sample Type
A healthcare professional will draw a small blood sample from a vein in your arm using a needle
Collection
Visit any participating lab location with a valid photo ID. The blood draw takes just a few minutes and you can resume normal activities immediately
Turnaround
Results are typically available within 1-3 business days and will be securely delivered to your online account
Understanding your results
A non-reactive (negative) result is normal and means no hepatitis C antibodies were detected in your blood. This indicates you have likely never been infected with the hepatitis C virus. A reactive (positive) result means antibodies to HCV were found, indicating exposure to the virus at some point. However, this doesn't necessarily mean you have an active infection. When antibodies are detected, the laboratory automatically performs additional RNA testing to determine if the virus is currently present in your body. Your lab report will include specific reference ranges and interpretation guidelines from the laboratory that processed your sample.
| Population | Reference Range | Notes |
|---|---|---|
| All adults | Non-reactive (Negative) | Normal result - no hepatitis C antibodies detected |
| All adults | Reactive (Positive) | Antibodies detected - requires follow-up RNA testing to determine infection status |
Reference ranges shown are general guidelines. Your lab report will include the specific reference range used by the laboratory that processed your sample, which is the authoritative range for interpreting your results.
What does a “Low” result mean?
A non-reactive result indicates no detectable hepatitis C antibodies, suggesting you have not been exposed to the virus. However, if exposure occurred within the past 8-11 weeks, antibodies may not yet be detectable.
What does a “High” result mean?
A reactive antibody test indicates exposure to hepatitis C virus. This may represent a current active infection, a past infection that was cleared naturally, or successful treatment. Automatic RNA testing will determine your current infection status.
Privacy & confidentiality
Your hepatitis C test results are completely confidential and will only be shared with you through your secure online account. Results are not shared with employers, insurance companies, or anyone else without your explicit consent. All testing is conducted in accordance with HIPAA privacy regulations to protect your personal health information.
Frequently asked questions
Related tests
CPT Code: 86803
This test may not be available in: NY, NJ, RI
This page is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider regarding any health concerns. LevelPanel does not diagnose, treat, or prescribe.
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Not sure if this is the right test? Contact our care team for guidance.