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Liver & Kidney

Kidney Function Panel (Renal Panel)

A comprehensive blood test that measures kidney function by evaluating waste filtration and electrolyte balance through multiple biomarkers.


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Blood

What this test measures

The Kidney Function Panel is a comprehensive blood test that evaluates how well the kidneys are performing their vital functions. The kidneys play a vital role in excreting waste products and toxins, such as urea, creatinine, and uric acid. They also regulate extracellular fluid volume, serum osmolality, and electrolyte concentrations and produce hormones such as erythropoietin, 1,25 dihydroxy vitamin D, and renin. This panel typically measures multiple biomarkers including blood urea nitrogen (BUN), creatinine, and essential electrolytes such as sodium, potassium, chloride, and carbon dioxide.

The Renal Function Panel Test measures blood urea nitrogen (BUN), creatinine, sodium, potassium, chloride, carbon dioxide, calcium, phosphorus, albumin, and glucose to evaluate kidney health. Doctors use this panel to monitor chronic kidney disease (CKD), assess electrolyte balance, and guide treatment decisions. By examining these various components together, healthcare providers can assess not only how effectively the kidneys are filtering waste from the blood but also how well they are maintaining the body's chemical balance. The test provides crucial information about kidney filtration capacity, electrolyte regulation, and overall metabolic health.

What's included

Blood Urea Nitrogen (BUN)
Creatinine
Estimated Glomerular Filtration Rate (eGFR)
BUN/Creatinine Ratio
Sodium
Potassium
Chloride
Carbon Dioxide (CO2)
Calcium
Phosphorus
Albumin
Glucose

Who should consider this test

You might consider this test if you are experiencing any of the following:

  • Individuals with risk factors for kidney disease such as diabetes, high blood pressure, or family history of kidney problems
  • Those experiencing symptoms that may indicate kidney dysfunction, including swelling in extremities, changes in urination patterns, or unexplained fatigue
  • People taking medications that may affect kidney function or require monitoring of kidney health
  • Individuals with cardiovascular disease, as kidney and heart health are closely interconnected
  • Those following up on previously abnormal kidney function tests or monitoring chronic kidney disease progression
  • Adults over 60 years of age, as kidney function naturally declines with age and regular monitoring becomes important

What to expect

Preparation

No fasting is typically required for this test, though some healthcare providers may recommend avoiding excessive protein intake or strenuous exercise for 24 hours before testing. Patients should inform their healthcare provider of all medications and supplements, as certain drugs may affect results. Maintaining normal hydration levels is important, as dehydration can influence BUN levels.

Sample Type

A small blood sample is drawn from a vein, typically in the arm. The procedure is quick and minimally invasive.

Collection

At the lab or collection site, a healthcare professional will clean the area and insert a small needle to draw blood into collection tubes. The entire process usually takes just a few minutes. No doctor visit required - individuals can visit any participating lab location.

Turnaround

Results are typically available within 1-2 business days. Test results will be delivered securely through an online portal or as specified during the ordering process.

Understanding your results

The Kidney Function Panel results should be interpreted as a comprehensive picture rather than individual values in isolation. The findings of a renal panel test are not diagnostic; rather, they indicate that there may be a problem with the kidneys and that additional testing is needed to make a diagnosis and determine the reason. The panel's results are usually weighed jointly rather than separately. Individual test results may be abnormal for reasons other than kidney disease, but when combined with risks and/or signs and symptoms, they may indicate the presence of renal disease. Healthcare providers will evaluate patterns across multiple biomarkers to assess kidney function and identify potential issues requiring further investigation or monitoring.

PopulationReference RangeNotes
Adult MalesBUN: 6-24 mg/dL, Creatinine: 0.7-1.3 mg/dL, eGFR: >60 mL/min/1.73m²Reference ranges may vary slightly based on laboratory methods and patient factors
Adult FemalesBUN: 6-24 mg/dL, Creatinine: 0.6-1.1 mg/dL, eGFR: >60 mL/min/1.73m²Lower creatinine ranges typically reflect generally lower muscle mass in females
BUN/Creatinine Ratio10:1 to 20:1This calculated ratio helps differentiate between various causes of kidney dysfunction
ElectrolytesSodium: 136-145 mEq/L, Potassium: 3.5-5.1 mEq/L, Chloride: 98-107 mEq/LElectrolyte balance is crucial for proper kidney and overall body function

Reference ranges shown are general guidelines. Your lab report will include the specific reference range used by the laboratory that processed your sample, which is the authoritative range for interpreting your results.

What does a “Low” result mean?

Low values in kidney function tests are less common but can be clinically significant. Low levels are also seen in trauma, surgery, opioids, malnutrition, and anabolic steroid use. Low BUN levels may indicate liver dysfunction, malnutrition, or overhydration, since BUN production depends on liver function and protein metabolism. Low creatinine levels might suggest decreased muscle mass, certain medications, or in rare cases, liver disease. When there is decreased formation of urea as seen in liver disease, there is a decrease in the BUN/Creatinine ratio. Low electrolyte levels can indicate various conditions affecting fluid balance or kidney regulation. These findings typically require correlation with other clinical information and may warrant additional testing to determine underlying causes.

What does a “High” result mean?

Elevated blood urea nitrogen may indicate kidney function problems. Like BUN, high blood creatinine levels often indicate kidney issues. Elevated results in kidney function tests may suggest various conditions affecting the kidneys' ability to filter waste and maintain proper fluid and electrolyte balance. Abnormal results may indicate kidney disease, dehydration, or metabolic imbalance. High BUN and creatinine levels together typically suggest impaired kidney filtration, while elevated BUN alone may indicate dehydration, high protein intake, or reduced blood flow to the kidneys. Electrolyte imbalances can reflect the kidneys' reduced ability to regulate body chemistry. However, elevated values can also result from factors unrelated to kidney disease, such as certain medications, dietary factors, or temporary conditions.

Privacy & confidentiality

All test orders are authorized and results reviewed by an independent, board-certified physician who is not the patient's personal doctor. At LevelPanel, we understand that kidney function testing can be a private health concern, and we're committed to protecting your confidentiality. Your kidney function test results are <u>not reported to your doctor</u> or healthcare provider unless you specifically choose to share them. The results are <u>not part of your medical records</u> maintained by your physician's office or health system. Additionally, since no doctor visit is required and you pay directly for testing, these results will <u>not appear on insurance statements</u> or explanation of benefits forms. We maintain strict privacy protocols to ensure your health information remains confidential. Your results are accessible only through your secure online account, and we never share your personal health data with employers, insurance companies, or third parties without your explicit consent. This private testing approach allows you to monitor your kidney health proactively, track changes over time, or seek additional medical consultation if needed, all while maintaining complete control over your health information. Whether you're monitoring kidney function due to family history, managing existing conditions, or simply taking a proactive approach to health, you can test with confidence knowing your privacy is protected.

Frequently asked questions

Related tests

Related conditions

CPT Code: 80069

This test may not be available in: NY, NJ, RI

This page is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider regarding any health concerns. LevelPanel does not diagnose, treat, or prescribe.

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