Men's Hormone Panel — Basic
A comprehensive assessment of key male hormones that measures total testosterone, bioavailable testosterone, and protein binding factors to evaluate hormonal health.
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What this test measures
This comprehensive hormone panel measures total testosterone (both free and protein-bound forms), free testosterone (the biologically active fraction), bioavailable testosterone (free plus weakly bound to albumin), sex hormone-binding globulin (SHBG), and albumin levels. In men, approximately 44% of testosterone is tightly bound to SHBG, 50% is loosely bound to albumin, 4% is bound to other proteins, and only 2% circulates freely. The free and albumin-bound fractions together comprise bioavailable testosterone, which represents the hormone readily available to tissues. Understanding these different forms is crucial because men with high SHBG may have normal total testosterone but low free testosterone, leading to symptoms despite seemingly normal lab values. Conversely, men with low SHBG may have adequate bioavailable testosterone even with borderline-low total levels.
What's included
Who should consider this test
You might consider this test if you are experiencing any of the following:
- Men experiencing persistent fatigue, low energy, or difficulty maintaining motivation despite adequate rest
- Those noticing decreased sex drive, erectile dysfunction, or changes in sexual performance
- Men observing loss of muscle mass, increased difficulty building or maintaining muscle, or unexplained weight gain
- Individuals dealing with mood changes, irritability, depression, or difficulty concentrating
- Men whose total testosterone results seemed normal but symptoms persist
- Those considering or monitoring testosterone replacement therapy
- Men with metabolic concerns like insulin resistance, diabetes, or obesity that may affect hormone levels
- Individuals seeking a comprehensive baseline assessment of their hormonal health
What to expect
Preparation
No fasting required. For most accurate results, schedule your test for morning hours (before 10 AM) when testosterone levels are typically at their highest. Avoid intense exercise 24 hours before testing.
Sample Type
A simple blood draw from a vein in your arm, similar to routine lab work
Collection
Visit any Quest Diagnostics location with your lab order. Present a valid ID and your test request. The blood draw takes approximately 5 minutes.
Turnaround
Results are typically available within 1-3 business days and will be securely delivered to your online account
Understanding your results
According to medical guidelines, normal total testosterone levels for adult males typically range from 300-1000 ng/dL, though optimal levels are often considered to be in the higher portion of this range. Free testosterone reference ranges commonly fall between 5-21 ng/dL, with levels below 5 ng/dL potentially indicating hormonal insufficiency. Your lab report will include the specific reference ranges used by the laboratory that processed your sample. It's important to consider all components together rather than viewing each result in isolation, as the relationship between total testosterone, SHBG, and bioavailable testosterone provides the most complete picture of hormonal status.
| Population | Reference Range | Notes |
|---|---|---|
| Adult men | 300-1000 ng/dL | Total testosterone; varies by time of day and age |
| Adult men | 5-21 ng/dL | Free testosterone; calculated values may vary between labs |
| Adult men | 110-400 ng/dL | Bioavailable testosterone for ages 20-69 |
| Adult men | 10-57 nmol/L | SHBG; increases with age, decreases with obesity |
| Adult men | 3.5-5.2 g/dL | Albumin; protein that binds testosterone |
Reference ranges shown are general guidelines. Your lab report will include the specific reference range used by the laboratory that processed your sample, which is the authoritative range for interpreting your results.
What does a “Low” result mean?
Low testosterone levels may indicate primary hypogonadism (testicular dysfunction), secondary hypogonadism (pituitary or hypothalamic issues), or age-related decline. Low SHBG often accompanies insulin resistance, obesity, metabolic syndrome, or hypothyroidism. Low albumin may suggest liver dysfunction, malnutrition, or chronic illness.
What does a “High” result mean?
Elevated testosterone levels may indicate testicular tumors, anabolic steroid use, or adrenal disorders. High SHBG can be associated with hyperthyroidism, liver disease, or aging, and may result in symptoms of low testosterone despite normal total levels. High albumin typically reflects good nutritional status.
Privacy & confidentiality
Your hormone test results are delivered securely to your private online account and are never shared with employers, insurance companies, or third parties without your explicit consent. All testing is conducted confidentially through HIPAA-compliant laboratories, ensuring your personal health information remains completely private.
Frequently asked questions
CPT Code: 84403, 84402, 84270, 82040
This test may not be available in: NY, NJ, RI
This page is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider regarding any health concerns. LevelPanel does not diagnose, treat, or prescribe.
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Not sure if this is the right test? Contact our care team for guidance.